Peak-Muscle.com  

Welcome to the Peak-Muscle.com forums.

You are currently viewing our boards as a guest which gives you limited access to view most discussions and access our other features. Come join us in on one of the best online fitness communities. We have 16,000 members that are likeminded towards a fitness, bodybuilding lifestyle. Registration is free and only takes but a few minutes. By joining our free community you will have access to communicate privately with other members (PM), respond to polls, upload content and access many other special features. You will be able to create threads to discuss and or create a fitness regimen. Or just bounce ideas off of some very knowledgeable members. So don't miss out. Registration is fast, simple and absolutely free so please, join our community today!

Register FAQ Members List Calendar Arcade Mark Forums Read
Go Back   Peak-Muscle.com > Bodybuilding and Fitness Discussion > Over 50 and beyond.
User Name
Password

Reply
 
Thread Tools Display Modes
Old 09-09-2019, 04:41 PM   #1
liftsiron
Administrator
 
liftsiron's Avatar
 

Join Date: Nov 2003
Location: Cimmeria
Posts: 18,384
liftsiron has a brilliant futureliftsiron has a brilliant futureliftsiron has a brilliant futureliftsiron has a brilliant futureliftsiron has a brilliant futureliftsiron has a brilliant futureliftsiron has a brilliant futureliftsiron has a brilliant futureliftsiron has a brilliant futureliftsiron has a brilliant futureliftsiron has a brilliant future
It might be possible to reverse a person’s biological age

This was posted by Druss on wcbb.



Home Science It might be possible to reverse a person’s biological age
It might be possible to reverse a person’s biological age

Science
It might be possible to reverse a person’s biological age

In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock’, which tracks a person’s biological age.
Avatar
Amit Malewar
2 days ago

Biological age is the objective assessment of an individual’s health status. Hypothetically, a ‘normal’ person’s biological age- – as far as appearance, performance, and functional capacity- ought to be equivalent to his chronological age. Until now, many scientists have endeavored to create systems to precisely determine people’s biological age.

In a recent study in California, scientists found that there is a possibility to reverse the process of ageing.

The results were really surprising, however scientists suggests that the findings are preliminary because the trial was small and did not include a control arm.

The study involved nine healthy volunteers, who were given a cocktail of three common drugs for a year- growth hormone and two diabetes medications. When scientists analysed marks on a person’s genomes, they found that the volunteers aged backwards- losing an average of 2.5 years from their biological ages.

The marks on their genomes represent their epigenetic clock, as well as their immune systems, actually improved despite the passing of time. Moreover, the volenteers’ immune systems also showed signs of rejuvenation.

Geneticist Steve Horvath at the University of California, Los Angeles, who conducted the epigenetic analysis said, “I’d expected to see slowing down of the clock, but not a reversal. That felt kind of futuristic.”

Cell biologist Wolfgang Wagner at the University of Aachen in Germany said, “It may be that there is an effect. But the results are not rock solid because the study is very small and not well controlled.”

The epigenetic clock is estimated by the body’s epigenome – a record of chemical changes to an organism’s DNA. As people age, chemical adjustments or labels are added to people’s DNA, and those change for the duration of their lives, so by taking a gander at those tags an individual’s natural age can be estimated.

Through this study, scientists actually wanted to observe how the growth hormone would change the tissue in the thymus gland, which is is crucial for efficient immune function. Various studies have shown that growth hormone stimulates regeneration of the thymus. But, this harmone can also lead to diabetes. Thus, the study included two widely used anti-diabetic drugs, dehydroepiandrosterone (DHEA) and metformin, in the treatment cocktail.

Scientists looked at four different measures of the epigenetic clock to understand the differing ages of each of the patients. They found that each volunteer had reversed significantly.

Horvath said, “This told me that the biological effect of the treatment was robust. What’s more, the effect persisted in the six participants who provided a final blood sample six months after stopping the trial.”

“Because we could follow the changes within each individual, and because the effect was so very strong in each of them, I am optimistic.”

Scientists now hope to test the same effects with more people, through a controlled study, and with different age groups, ethnicity and with women.
JOURNALDOI: 10.1038/d41586-019-02638-w

TOPICSAgeing
__________________
ADMIN/OWNER@Peak-Muscle
liftsiron is offline   Reply With Quote
Old 09-10-2019, 12:07 PM   #2
Augerdog
Vet
 
Augerdog's Avatar
 

Join Date: Mar 2014
Posts: 190
Augerdog has a spectacular aura aboutAugerdog has a spectacular aura about
I volunteer!
Augerdog is offline   Reply With Quote
Old 09-11-2019, 07:39 AM   #3
Augerdog
Vet
 
Augerdog's Avatar
 

Join Date: Mar 2014
Posts: 190
Augerdog has a spectacular aura aboutAugerdog has a spectacular aura about
On the way home last night I heard about this again on fox health news radio
Augerdog is offline   Reply With Quote
Old 09-23-2019, 08:30 AM   #4
b52
Moderator
 
b52's Avatar
 

Join Date: Oct 2006
Posts: 2,389
b52 is a splendid one to beholdb52 is a splendid one to beholdb52 is a splendid one to beholdb52 is a splendid one to beholdb52 is a splendid one to beholdb52 is a splendid one to beholdb52 is a splendid one to behold
I was reading about this the other day. Found it fascinating.
b52 is offline   Reply With Quote
Old 09-23-2019, 09:52 AM   #5
millenium girl
Moderator
 
millenium girl's Avatar
 

Join Date: Apr 2006
Posts: 3,178
millenium girl is a name known to allmillenium girl is a name known to allmillenium girl is a name known to allmillenium girl is a name known to allmillenium girl is a name known to allmillenium girl is a name known to all
Quote:
Originally Posted by Augerdog View Post
I volunteer!
So do I
millenium girl is offline   Reply With Quote
Old 09-23-2019, 05:20 PM   #6
Dakota
VET
 
Dakota's Avatar
 

Join Date: Feb 2017
Posts: 1,991
Dakota is a name known to allDakota is a name known to allDakota is a name known to allDakota is a name known to allDakota is a name known to allDakota is a name known to all
Wow.

Can you imagine the demand??
__________________
The older I get the better I used to be.
Dakota is offline   Reply With Quote
Reply

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off

Forum Jump


All times are GMT -5. The time now is 03:59 AM.


Powered by: vBulletin Version 3.8.11
Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.