Everyone by now has heard of Arimidex/Liquidex(ie anastrozole) but there are a couple others with slightly better estrogen suppression values as well as slight differences in the way they affect the endocrine system.
The other two 3rd generation Anti-e's are letrozole(femara) and exemestane(aromasin). Letrozole and anastrozole are aromatase inhibitors while exemestane is considered an aromatase inactivator.
While all of these seem to exert an effect on our LH/FSH levels, some also have an effect on IGF-1 levels as well. According to some studies for example, anastrzole was shown to reduce IGF-1 levels by 18%(note 1), which is likely due to reduced estrogen. Another abstract shows that letrozole actually increased IGF-1 levels by an average of 24%(note 2).
Following are some detailed descriptions of the 3 products.
The other two 3rd generation Anti-e's are letrozole(femara) and exemestane(aromasin). Letrozole and anastrozole are aromatase inhibitors while exemestane is considered an aromatase inactivator.
While all of these seem to exert an effect on our LH/FSH levels, some also have an effect on IGF-1 levels as well. According to some studies for example, anastrzole was shown to reduce IGF-1 levels by 18%(note 1), which is likely due to reduced estrogen. Another abstract shows that letrozole actually increased IGF-1 levels by an average of 24%(note 2).
Following are some detailed descriptions of the 3 products.
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