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Old 09-29-2019, 06:55 PM   #1
jrod
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Age and fat loss

https://www.eurekalert.org/pub_relea...-nss090619.php




News Release 9-Sep-2019
New study shows why people gain weight as they get older

Karolinska Institutet

Many people struggle to keep their weight in check as they get older. Now new research at Karolinska Institutet in Sweden has uncovered why that is: Lipid turnover in the fat tissue decreases during ageing and makes it easier to gain weight, even if we don't eat more or exercise less than before. The study is published in the journal Nature Medicine.

The scientists studied the fat cells in 54 men and women over an average period of 13 years. In that time, all subjects, regardless of whether they gained or lost weight, showed decreases in lipid turnover in the fat tissue, that is the rate at which lipid (or fat) in the fat cells is removed and stored. Those who didn't compensate for that by eating less calories gained weight by an average of 20 percent, according to the study which was done in collaboration with researchers at Uppsala University in Sweden and University of Lyon in France.

The researchers also examined lipid turnover in 41 women who underwent bariatric surgery and how the lipid turnover rate affected their ability to keep the weight off four to seven years after surgery. The result showed that only those who had a low rate before the surgery managed to increase their lipid turnover and maintain their weight loss. The researchers believe these people may have had more room to increase their lipid turnover than those who already had a high-level pre-surgery.

"The results indicate for the first time that processes in our fat tissue regulate changes in body weight during ageing in a way that is independent of other factors," says Peter Arner, professor at the Department of Medicine in Huddinge at Karolinska Institutet and one of the study's main authors. "This could open up new ways to treat obesity."

Prior studies have shown that one way to speed up the lipid turnover in the fat tissue is to exercise more. This new research supports that notion and further indicates that the long-term result of weight-loss surgery would improve if combined with increased physical activity.

"Obesity and obesity-related diseases have become a global problem," says Kirsty Spalding, senior researcher at the Department of Cell and Molecular Biology at Karolinska Institutet and another of the study's main authors. "Understanding lipid dynamics and what regulates the size of the fat mass in humans has never been more relevant."

###

The study was financed by grants from the Stockholm County Council, the Swedish Research Council, the Strategic Research Program for Diabetes at Karolinska Institutet, the Novo Nordisk Foundation, the Swedish Diabetes Foundation, Karolinska Institutet-Astra Zeneca Integrated Cardiometabolic Center, the Vallee Foundation, the Swedish Society of Medicine, the Erling-Persson Family foundation and IXXI.

Publication: "Adipose lipid turnover and long term changes in body weight," Peter Arner, Samuel Bernard, Lena Appelsved, Keng-Yeh Fu, Daniel Andersson, Mehran Salehpour, Anders Thorell, Mikael Rydén, Kirsty Spalding, Nature Medicine, online September 9, 2019, doi: 10.1038/s41591-019-0565-5
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Old 09-30-2019, 05:15 AM   #2
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Interesting read, however in my case I eat the same and exercise close to the same that I did 30 years ago and I am roughly the same weight and bodyfat %. I assume this study used semi couch potatoes as their participants?
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Old 10-02-2019, 06:38 AM   #3
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I'm in the same boat as Lifts. My body fat stays in the low teens year round
But as Lifts stated, I've been lifting since the late 60's. And training seriously since '84. So I have a very solid foundation.
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Old 10-02-2019, 06:50 AM   #4
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This is me just now. I'm bloated here from two mugs of coffee, 8 eggs, 4 toast, and 4 bacon breakfast. Probably around 255. I'm out of shape here. I haven't done a shot, trt or otherwise for 5 weeks now. Been working 12 hour days past week and a half. Training is only 1 exercise per body part, 3 to 5 sets to failure depending on how tired I am until I get more free time. But you get the idea.
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Old 10-02-2019, 03:25 PM   #5
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I haven't noticed a drop off & I'll be 56 in a month. But I exercise often, so. Exercise - with added in weight training - is the Fountain of Youth.
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Old 10-03-2019, 06:11 AM   #6
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I think for men that weight train the tendency is not so much to gain weight and get fat as it is to lose weight and get smaller. Especially looking at the pro's.
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Old 10-03-2019, 01:42 PM   #7
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I guess we are all proof of the studies thesis, that even old farts stay leaner by exercise of some sort.
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Old 12-10-2019, 04:21 PM   #8
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Quote:
Originally Posted by Roughrydr View Post
This is me just now. I'm bloated here from two mugs of coffee, 8 eggs, 4 toast, and 4 bacon breakfast. Probably around 255. I'm out of shape here. I haven't done a shot, trt or otherwise for 5 weeks now. Been working 12 hour days past week and a half. Training is only 1 exercise per body part, 3 to 5 sets to failure depending on how tired I am until I get more free time. But you get the idea.
Not bad for an old fart! 👍🏼
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Old 12-10-2019, 04:35 PM   #9
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I see a lot of fat fucks that are older at the gym that are regulars..
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