OBJECTIVE: It is known that total parenteral nutrition (TPN) causes liver damage by various mechanisms and leads to an increase of transaminases and obstructional enzymes. From this aspect TPN can be considered an external factor which causes liver damage. In our investigation we wanted to find out whether parenteral administration of essential phospholipids (EPL) can have a protective effect on this damage.
PATIENTS AND METHODS: Our investigation comprised 20 patients where TPN was indicated, usually on account of severe acute exacerbation of a non-specific inflammation of the gut. The patients were divided into two groups. Ten patients were treated by intravenous administration of essential phospholipids (Essentiale, Aventis), 50 mg every 6 hours for a period of two weeks. The control group comprised ten patients without hepatoprotection. The bilirubin, ALT, AST, GMT, ALP values were assessed before the initiation of the study, on the seventh and fourteenth day. The results were statistically processed by the paired and non-paired t-test.
RESULTS: The baseline results of the mentioned tests did not differ significantly between groups. Bilirubin and AST did not change significantly during the investigation. In the control group we found, as compared with baseline values, a significantly increase of ALT on the seventh and fourteenth day, a significantly increase of GMT on the seventh and fourteenth day and a slight non-significant rise of ALP on the fourteenth day. In the ELP treated group, as compared with baseline values, a significant rise of ALT occurred on the fourteenth day. We did not observe a significant rise of GMT and ALP. Between the ELP treated and control group a significant increase of GMT and ALP occurred in the control group, the other values did not differ between groups.
CONCLUSION: Parenteral EPL administration can have a favourable effect on liver damage caused by TPN, associated with cholestasis and biliary sludge. This conclusion can be hypothetically explained by improved bile fluidity and protection of the bile pole of the hepatocyte by essential phospholipids. Therefore their administration during TPN can be recommended.
llewellyn explains in either 9th or his 10th edition that liver support breaks down the greater amount of steroid. i'll have to get more details and post back the science behind it.
llewellyn explains in either 9th or his 10th edition that liver support breaks down the greater amount of steroid. i'll have to get more details and post back the science behind it.
llewellyn explains in either 9th or his 10th edition that liver support breaks down the greater amount of steroid. i'll have to get more details and post back the science behind it.
I think that might be just milk thistle, not all liver supps.
I take Milk Thistle all year long. It's more a detox than a protector but it works really well considering the liver is a filter.
Anyone on a high protein diet should take liver supps.The amount of chemical waste and stress put on the liver from protein breakdown is far from healthy.
Not sure how they work. Can some of you bros shed some light on it i/e, phospholipid m essetiale-300mgs tabs
Thanks,
Z-
I dont know the exact chemical action they perform to cleanse the liver,But im guessing its something to do with either the drugs containing detoxing agents or enzymes that perform benificial actions.
Lets look at the Phytochemical and nutrient content of milk thistle.
Phytochemical:
Apigenin, betacarotene, fumaric acid, kaempferol, naringenin, quercetin, siladrin, silybin, silychristin, silydianin, silymarin, silymonin, taxifolin.
Nutrients:
Calcium, essential fatty acids, iron, magnesium, magnese, phosphorus, potassium, selenium, zinc.
The action of milk thistle: Protects the liver from toxins and pollutants by preventing free radical damage and stimulates the production of new liver cells.Also inhibits COX-2 formation.
NAC and ALA, as for protein breakdown, although BUN levels can be a concern for those at high risk of liver and kidney disease high protein diets for anyone without a pre-existing condition are perfectly fine. If you have any data to suggest liver issues in healthy people due to protein intake I'm all for reading it.
NAC and ALA, as for protein breakdown, although BUN levels can be a concern for those at high risk of liver and kidney disease high protein diets for anyone without a pre-existing condition are perfectly fine. If you have any data to suggest liver issues in healthy people due to protein intake I'm all for reading it.
One day the doc at work asked me if I was weightlifting ... I didn't know what to say but I replied "yes", he asked "Are you taking any supplements?" ... I could feel the heat (I was juicing at the time), I said "whey protein, BCAA's, Krill Oil, ....". He said that the creatinine levels in my blood were elevated. What a relief lol.
One day the doc at work asked me if I was weightlifting ... I didn't know what to say but I replied "yes", he asked "Are you taking any supplements?" ... I could feel the heat (I was juicing at the time), I said "whey protein, BCAA's, Krill Oil, ....". He said that the creatinine levels in my blood were elevated. What a relief lol.
Yup that's normal for anyone doing strenuous exercise especially anyone with above normal musculature. Nothing to worry about in your case.
I personally use Liv52, Milk Thistle, and Vit.E, when taking orals....and would be a wise idea for everyone to do the same!
^^^ THIS ^^^ With some ALA.. I'm glad someone is paying attention!!! Trust me I've taken Chemo for my liver and this is what I was told to take the entire time on Chemo..
^^^ THIS ^^^ With some ALA.. I'm glad someone is paying attention!!! Trust me I've taken Chemo for my liver and this is what I was told to take the entire time on Chemo..
Hey Freeze ALA, does it come in a powdered capsule, or liquid cap?
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